April 30, 2008 -- Young women taking the common epilepsy drugepilepsy drug Anticonvulsants work by calming hyperactivity in the brain in various ways. For this reason, some of these drugs are used to treat epilepsy, prevent migraines, and treat other brain disorders. They are often prescribed for people who have rapid cycling -- four or more episodes of mania and depression in a year. › guide › anticonvulsant-medication

Anticonvulsants for Bipolar Disorder: Types and Side Effects - WebMD

Dilantin may risk bone loss and fracture with long-term use.

Do seizure medications cause osteoporosis?

Some people who take epilepsy medicines are at risk of decreased bone mineral density. This condition is called osteoporosis. It is a condition that can weaken bones, making them fragile and more likely to break.

Does phenytoin cause bone loss?

Antiepileptic Drugs

Certain anticonvulsants may cause bone loss. The medications most commonly associated with osteoporosis include phenytoin, phenobarbital, carbamazepine, and primidone.

What drugs can affect bone density?

Many drugs can affect bone metabolism. As an example, heparin, warfarin, cyclosporine, glucocorticoids, medroxyprogesterone acetate, cancer drugs, and thyroid hormone can cause bone loss, while thiazide diuretics can minimize bone loss [1,2]. This topic will review the skeletal effects of some of these drugs.

What medications can increase risk of osteoporosis?

Which medicines can cause bone loss?

• Glucocorticoids, also called steroids, such as cortisone and prednisone. ...
• Some medicines such as phenytoin and phenobarbital, used to treat epilepsy.
• Gonadotropin-releasing hormone agonists (GnRH agonists), such as goserelin acetate and leuprolide acetate.

Osteoporosis: Causes, Symptoms & Treatment

19 related questions found

What causes rapid loss of bone density?

However, there are a number of medical conditions and medications that can cause more rapid bone loss — the most common conditions are hyperparathyroidism, hyperthyroidism, vitamin D deficiency and celiac disease, and the most common medications are steroids and aromatase inhibitors.

What is the new drug for osteoporosis?

Romosozumab (Evenity).

This is the newest bone-building medication to treat osteoporosis.

What medications interfere with calcium absorption?

Well, you should know that there are several medications that can interfere with calcium absorption in your body. Common culprits include medications used to treat heartburn and “gastroesophageal reflux disorder” (GERD), such as omeprazole (Prilosec), lansoprazole (Prevacid), and esomeprazole (Nexium).

Can bone loss from osteoporosis be reversed?

Can osteoporosis be reversed without medications? Your doctor diagnoses osteoporosis based on bone density loss. You can have different degrees of the condition, and catching it early can help you prevent the condition from worsening. You cannot reverse bone loss on your own.

What drugs deplete calcium?

Low calcium can occur with tablets like ibandronate (Boniva) and alendronate (Fosamax), but it's more likely to occur with high doses of strong bisphosphonates, like zoledronic acid (Zometa), an drug given by IV (intravenous infusion).

Does phenytoin affect bone density?

Anticonvulsant therapy causes changes in calcium and bone metabolism and may lead to decreased bone mass with the risk of osteoporotic fractures. The two widely used antiepileptic drugs phenytoin and carbamazepine are recognized to have direct effects on bone cells.

Does smoking contribute to osteoporosis?

Cigarette smoking causes heart disease, lung and esophageal cancer, and chronic lung disease. Additionally, several research studies have identified smoking as a risk factor for osteoporosis and bone fracture.

How can I rebuild my bones?

10 Natural Ways to Build Healthy Bones

1. Eat Lots of Vegetables. ...
2. Perform Strength Training and Weight-Bearing Exercises. ...
3. Consume Enough Protein. ...
4. Eat High-Calcium Foods Throughout the Day. ...
5. Get Plenty of Vitamin D and Vitamin K. ...
6. Avoid Very Low-Calorie Diets. ...
7. Consider Taking a Collagen Supplement. ...
8. Maintain a Stable, Healthy Weight.

Does epilepsy affect your bones?

Diseases of the bone are becoming increasingly prevalent. Persons with epilepsy treated with antiepileptic drugs (AEDs) are at greater risk as evidenced by changes in bone turnover, osteoporosis, alterations in bone quality, and fracture.

What antiepileptic decreases bone density?

Antiepileptic Drugs Associated with Bone Disease

The AEDs most commonly associated with altered bone metabolism and decreased bone density are inducers of the cytochrome P450 enzyme system, including phenytoin (PHT), carbamazepine (CBZ), primidone (PRM), and phenobarbital (PB) (6, 7,9,23,24,34).

Can you take vitamin D with epilepsy drugs?

Some anti-seizure medications interfere with how vitamin D is processed in the body. Supplemental vitamin D may be necessary for people who have these risk factors to maintain normal blood levels. A study published in 2012 showed that correcting vitamin D deficiency reduced seizures in people with epilepsy.

What not to eat if you have osteoporosis?

7 Foods to Avoid When You Have Osteoporosis

• Salt. ...
• Caffeine. ...
• Soda. ...
• Red Meat. ...
• Alcohol. ...
• Wheat Bran. ...
• Liver and Fish Liver Oil.

How can I increase my bone density after 60?

5 ways to build strong bones as you age

1. Think calcium. Women up to age 50 and men up to age 70 need 1,000 milligrams daily; women over 50 and men over 70 should get 1,200 milligrams daily.
2. And vitamin D. ...
3. Exercise. ...
4. Don't smoke. ...
5. Drink alcohol moderately, if at all. ...
6. Remember protein. ...
7. Maintain an appropriate body weight.

What is the best and safest treatment for osteoporosis 2020?

Bisphosphonates are usually the first choice for osteoporosis treatment. These include: Alendronate (Fosamax), a weekly pill. Risedronate (Actonel), a weekly or monthly pill.

Can BP meds cause osteoporosis?

CHICAGO (Reuters) - Powerful diuretics used to control blood pressure can also steal calcium from the bones and cause significant bone loss in men who take them, researchers reported on Monday.

What are 4 worst blood pressure drugs?

Both Yancy and Clements point out that those medications include: thiazide diuretics (chlorthalidone, hydrochlorothiazide) ACE inhibitors (benazepril, zofenopril, lisinopril, and many others) calcium channel blockers (amlodipine, diltiazem)

Do statins cause bone loss?

New research suggests that there is a relationship between statin use and the chances of receiving a diagnosis of osteoporosis, a condition that weakens bones.

How can I increase my bone density without medication?

Keep reading for tips on increasing bone density naturally.

1. Weightlifting and strength training. ...
2. Eating more vegetables. ...
3. Consuming calcium throughout the day. ...
4. Eating foods rich in vitamins D and K. ...
5. Maintaining a healthy weight. ...
6. Avoiding a low calorie diet. ...
7. Eating more protein. ...
8. Eating foods rich in omega-3 fatty acids.

What is the life expectancy of a person with osteoporosis?

The average life expectancy of osteoporosis patients is in excess of 15 years in women younger than 75 years and in men younger than 60 years, highlighting the importance of developing tools for long-term management.

Can bone density be rebuilt?

The amount of bone mineral density (BMD) that a person with osteoporosis can regain varies from person to person. However once a significant amount of bone density has been lost, it is hard to replace.