Pantoprazole sodium sesquihydrate is a white to off-white crystalline powder and is racemic. Pantoprazole has weakly basic and acidic properties. Pantoprazole sodium sesquihydrate is freely soluble in water, very slightly soluble in phosphate buffer at pH 7.4, and practically insoluble in n-hexane.

What is pantoprazole sodium 40 mg used for?

Pantoprazole is used to treat damage from gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube between the throat and stomach) in adults and children 5 years of age and older.

What are the side effects of pantoprazole sodium 20 mg?

Pantoprazole side effects

• headache.
• diarrhea.
• stomach pain.
• nausea or vomiting.
• gas.
• dizziness.
• joint pain.

Why is it bad to take pantoprazole?

Pantoprazole may increase your risk of having fractures of the hip, wrist, and spine. This is more likely if you take several doses per day or use it for one year or more. Call your doctor right away if you have severe bone pain or are unable to walk or sit normally.

How long should I take pantoprazole 40 mg?

Adults—40 milligrams (mg) once a day for up to 8 weeks. Your doctor may want you to take pantoprazole for more than 8 weeks for certain conditions. Children 5 years of age and older weighing 40 kilograms (kg) or more—40 mg once a day for up to 8 weeks.

Pantoprazole ( Protonix 40 mg ): What is Pantoprazole Used For, Dosage, Side Effects & Precautions?

38 related questions found

Can I drink coffee while taking pantoprazole?

You can eat and drink normally while taking pantoprazole, but it's best to take it an hour before a meal. It's best to avoid foods that seem to make your symptoms worse, such as rich, spicy and fatty foods. It also helps to cut down on caffeinated drinks, such as tea, coffee and cola, as well as alcohol.

What happens if I take pantoprazole after eating?

Pantoprazole can be taken before or after food, although taking it before food is preferable. If you forget to take a dose at your usual time, you can take it when you remember (unless it is nearly time for your next dose, in which case leave out the missed dose).

Can pantoprazole cause weight gain?

You may have weight gain while you're taking pantoprazole oral tablets. Both weight gain and weight loss were reported after the drug's initial studies were done. Additionally, you may gain weight if you have edema (swelling) or bloating, which are possible side effects of pantoprazole.

Is pantoprazole the same as Zantac?

Protonix and Zantac belong to different drug classes. Protonix is a proton pump inhibitor (PPI) and Zantac is a H2 (histamine-2) receptor blocker. Protonix is available by prescription while Zantac is available over-the-counter (OTC) and as a generic.

Does pantoprazole raise blood pressure?

Omeprazole, lansoprazole and pantoprazole had no effect on blood pressure and electrocardiogram of anesthetized rat. Pharmacol Res. 2008 Jul;58(1):65-71. doi: 10.1016/j.

How safe is pantoprazole?

PPI have minimal side effects and few slight drug interactions and are considered safe for long term treatment. Pantoprazole is significantly effective both for acute and long-term treatment with excellent control of relapse and symptoms. It is well tolerated even for long-term therapy and its tolerability is optimal.

Should pantoprazole be taken on an empty stomach?

You can take PROTONIX tablets with food or on an empty stomach. Swallow PROTONIX tablets whole. If you have trouble swallowing a PROTONIX 40 mg tablet, you can take two 20 mg tablets instead. Do not split, chew, or crush PROTONIX tablets.

Can pantoprazole cause kidney damage?

The use of proton pump inhibitors – including Prevacid (lansoprazole), Prilosec (omeprazole), Protonix (pantoprazole), and Nexium (esomeprazole) – has been linked to an increased risk of kidney damage, kidney failure, and other serious side effects.

What symptoms does pantoprazole treat?

This medication relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. It helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Pantoprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).

Does pantoprazole work immediately?

The medication takes approximately two and a half hours to begin working, so it won't be effective for current symptoms. However, patients who need immediate relief from their acid reflux symptoms can combine pantoprazole with fast-acting Tums or Maalox to reduce the amount of acid.

Is it OK to take pantoprazole at night?

Protonix was first approved by the U.S. Food and Drug Administration (FDA) in 1985 and is considered a first-generation proton pump inhibitor; the generic pantoprazole was introduced following the expiration of the Protonix patent.

Is there a recall on pantoprazole?

Jubilant Cadista Pharmaceuticals Inc. is recalling 12,960 bottles of pantoprazole sodium delayed-release tablets, 40 mg, because of dark brown discoloration on the edges of tablets. The recall was included in the April 10, 2019, US Food and Drug Administration (FDA) Enforcement Report.

What is the meaning of pantoprazole?

Pantoprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach. Pantoprazole is used to treat erosive esophagitis (damage to the esophagus from stomach acid caused by gastroesophageal reflux disease, or GERD) in adults and children who are at least 5 years old.

What is the generic drug for pantoprazole?

Pantoprazole is the generic name for Protonix and can only be purchased with a prescription. It is FDA-approved to treat GERD in adults and children aged 5 years and older. Pantoprazole is supplied as a delayed-release tablet or liquid suspension.

Can pantoprazole cause a cough?

Since you had dramatic improvement with pantoprazole, it's likely that GERD is the major cause of the cough. But exacerbations of the heart rate are a known side-effect of pantoprazole, and it might be due to magnesium deficiency.

Does pantoprazole cause liver damage?

Pantoprazole therapy is associated with a low rate of transient and asymptomatic serum aminotransferase elevations and is a rare cause of clinically apparent liver injury.

How good is pantoprazole?

Pantoprazole has an average rating of 5.1 out of 10 from a total of 327 ratings on Drugs.com. 38% of reviewers reported a positive effect, while 47% reported a negative effect.

Can pantoprazole cause leg cramps?

low magnesium--dizziness, fast or irregular heart rate, tremors (shaking) or jerking muscle movements, feeling jittery, muscle cramps, muscle spasms in your hands and feet, cough or choking feeling; or.

What foods neutralize stomach acid?

Here are five foods to try.

• Bananas. This low-acid fruit can help those with acid reflux by coating an irritated esophageal lining and thereby helping to combat discomfort. ...
• Melons. Like bananas, melons also are a highly alkaline fruit. ...
• Oatmeal. ...
• Yogurt. ...
• Green Vegetables.

Can I take vitamins with pantoprazole?

No interactions were found between Celebrate Multivitamin and pantoprazole. This does not necessarily mean no interactions exist. Always consult your healthcare provider.