Doxazosin belongs to a group of medicines called alpha-blockers. It's used to treat high blood pressure and symptoms of an enlarged prostate (benign prostatic enlargement). This medicine is only available on prescription and comes as tablets.

What are the long term side effects of doxazosin?

If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks.

Why do you have to take doxazosin at night?

Bedtime administration of doxazosin appears to be safe and effective in reducing morning hypertension as measured by HBP. This finding also demonstrates that HBP taken in the morning has a stronger predictive power for the albuminuria level than does CBP.

Who should not take doxazosin?

talk to your doctor about the risks and benefits of taking doxazosin if you are 65 years of age or older. Older adults should not usually take doxazosin to treat high blood pressure, because it is not as safe as other medications that can be used to treat the same condition.

When should you not take doxazosin?

Do not take DOXAZOSIN if you: are allergic to doxazosin, other types of quinazolines (such as prazosin or terazosin) or any of the other ingredients of DOXAZOSIN tablets listed in section 6. This may have been itching, reddening of the skin or difficulty in breathing.

Alpha blockers: Prazosin, doxazosin, alfuzosin, tamsulosin (...osin drugs)

36 related questions found

What are 4 worst blood pressure drugs?

Both Yancy and Clements point out that those medications include: thiazide diuretics (chlorthalidone, hydrochlorothiazide) ACE inhibitors (benazepril, zofenopril, lisinopril, and many others) calcium channel blockers (amlodipine, diltiazem)

Does doxazosin make you urinate more?

Doxazosin lowers blood pressure by relaxing your blood vessels so blood can pass through more easily. Doxazosin helps reduce the symptoms of an enlarged prostate gland by relaxing the muscle around the bladder and prostate gland so you can pee more easily.

Does doxazosin cause weight gain?

While patients treated with doxazosin tend to gain weight, patients on placebo therapy lost weight. The Treatment of Mild Hypertension Study (TOMHS) trial is a notable exception for the trend towards weight gain [14].

Can doxazosin cause heart failure?

Conclusion. In high risk hypertensive patients, doxazosin was associated with a higher incidence of stroke and cardiovascular disease events, especially congestive heart failure, than was chlorthalidone.

How good is doxazosin?

Doxazosin has an average rating of 5.5 out of 10 from a total of 21 ratings for the treatment of High Blood Pressure. 29% of reviewers reported a positive effect, while 29% reported a negative effect.

Does doxazosin lower PSA?

The alpha-blocker class of medicines includes tamsulosin (Flomax), terazosin, and doxazosin. These agents do not have any significant influence on the value of PSA for the purpose of screening for prostate cancer.

Does doxazosin help erectile dysfunction?

In these patients, the doxazosin association with a dosage of 4 mg allowed for a statistically significant improvement of the erectile deficit: in particular, patients reported quicker erections and a constant erection during the entire intercourse.

How quickly does doxazosin work?

Blood levels of doxazosin reach a peak within two to three hours of an oral dose. The blood pressure-lowering effect occurs within one to six hours of a dose of doxazosin. Relief from symptoms of BPH and an increase in urine flow have been reported as early as one week after the initiation of doxazosin.

Does doxazosin affect sleep?

Examples: alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), silodosin (Rapaflo), terazosin (Hytrin) and tamsulosin (Flomax). How they can cause insomnia: Alpha-blockers are linked to decreased REM (rapid eye movement) sleep — the stage of sleep when people dream — and daytime sedation or sleepiness.

What is an alternative to doxazosin?

Doxazosin may cost as little as $10 per month. Hytrin, another generic drug, also works well. Both drugs are nonselective alpha-1 blockers, which means they can lower a person's blood pressure.

Does doxazosin slow heart rate?

Four hours following drug intake, heart rate and blood pressure were measured at rest and during exercise. Results: Both doxazosin and urapidil decreased blood pressure to the same extent. Compared to placebo, resting heart rate was significantly increased by doxazosin (+25%, P < 0.05) but not by urapidil (+12%, n.s.).

Is doxazosin good for the heart?

Treatment with doxazosin can lower blood pressure, reduce the levels of atherogenic lipids, increase the levels of cardioprotective lipids, reduce hyperinsulinaemia, insulin resistance and glucose intolerance, increase fibrinolysis, inhibit platelet aggregation, attenuate the adverse haemodynamic and haemostatic ...

Can doxazosin cause stroke?

In high risk hypertensive patients, doxazosin was associated with a higher incidence of stroke and cardiovascular disease events, especially congestive heart failure, than was chlorthalidone.

Can doxazosin cause atrial fibrillation?

However, the incidence of new atrial fibrillation or atrial flutter in 6,392 patients treated with doxazosin was significantly increased 1.3 times than in 11,695 patients treated with chlorthalidone (20).

Does doxazosin cause hair loss?

Musculoskeletal System: muscle cramps, muscle weakness. Psychiatric: agitation, loss of appetite, nervousness. Respiratory System: difficulty breathing (bronchospasm) aggravated. Skin Disorders: hair loss, hives, skin rash, severe itching.

Can you take doxazosin with Viagra?

Talk to your doctor before using sildenafil together with doxazosin. Combining these medications can lower your blood pressure and increase the risk of dizziness, lightheadedness, fainting, flushing, headache, and nasal congestion.

Can doxazosin cause water retention?

shortness of breath, diarrhea, abdominal pain, edema (fluid accumulation) and.

Does doxazosin affect vision?

Get medical help right away if you have any very serious side effects, including: vision changes, chest pain, jaw/left arm pain, weakness on one side of the body, slurred speech, confusion. Rarely, males may have a painful or prolonged erection lasting 4 or more hours.

How safe is doxazosin?

Doxazosin may cause a sudden drop in your blood pressure, which could lead to dizziness or fainting, usually within 2 to 6 hours after you take it. This risk is higher when you first start taking this drug, after your doctor increases your dose, or if you restart treatment after you stop taking it.

Does doxazosin raise blood sugar?

Following 26 weeks of treatment with doxazosin, supine and standing blood pressures were significantly decreased at a final mean daily dose of 6.4 mg. Blood glucose levels were significantly lower at 26 weeks than after the initial placebo period (p < 0.05) or after 4 weeks' treatment with doxazosin (p < 0.001).