COVID-19Common question

Is AstraZeneca COVID-19 vaccine approved by the FDA?

The AstraZeneca vaccine is not authorized for use in the U.S., but FDA understands that these AstraZeneca lots, or vaccine made from the lots, will now be exported for use.

Whaat happens if you mix AstraZeneca and Pfizer COVID-19 vaccines?

Researchers studied mixing and matching Pfizer's vaccine with AstraZeneca's, which is made using similar technology as J&J's. There, too, researchers found that people who got an AstraZeneca shot followed by Pfizer four weeks later produced more antibodies than those who received two AstraZeneca shots.

Who should not get the Moderna COVID-19 vaccine?

If you have had a severe allergic reaction (anaphylaxis) or an immediate allergic reaction, even if it was not severe, to any ingredient in an mRNA COVID-19 vaccine (such as polyethylene glycol), you should not get an mRNA COVID-19 vaccine.

Can I mix and match COVID-19 booster vaccines?

Boosters are now available for the three COVID-19 vaccines, made by Pfizer-BioNTech, Moderna and Johnson & Johnson. And the Centers for Disease Control and Prevention (CDC) has given the green light for safely mixing and matching the shots.

What vector is used in the AstraZeneca and Johnson & Johnson COVID-19 vaccines?

The virus vector being used in the Johnson & Johnson and AstraZeneca vaccines is an adenovirus, a common type of virus that typically causes mild cold symptoms when it infects someone.

COVID-19 viral vector vaccines inject a harmless adenovirus vector

Severe illness after vaccination

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How does the Johnson and Johnson COVID-19 vaccine work?

The Johnson & Johnson product is an adenovirus vaccine or a viral vector vaccine. Here is how it works.

The Johnson & Johnson vaccine delivers the virus' DNA to your cells to make the spike protein. An adenovirus acts as a delivery vehicle used to carry the coronavirus genetic material (DNA).

What are the ingredients in the Janssen COVID-19 vaccine?

The Janssen COVID-19 Vaccine includes the following ingredients: recombinant, replication-incompetent adenovirus type 26 expressing the SARS-CoV-2 spike protein, citric acid monohydrate, trisodium citrate dihydrate, ethanol, 2-hydroxypropyl-β-cyclodextrin (HBCD), polysorbate-80, sodium chloride.

Is it safe to take a different COVID-19 booster shot?

The study found that boosting with a different vaccine is safe, and that boosters increased antibody levels no matter the combination.

Can I get a different COVID-19 vaccine booster shot?

Notably, the FDA and CDC also authorized a “mix-and-match” strategy, enabling eligible Americans to get a booster shot from a brand different from their original vaccine.

Can you get a different COVID-19 vaccine booster?

Mixing and matching is OK for boosters Through the FDA's authorization and the CDC's recommendation, heterologous boosting—aka “mixing and matching”—is allowed with a single dose of any of the authorized COVID-19 vaccine boosters.

Can I get the COVID-19 vaccine if I have an underlying condition?

People with underlying medical conditions can receive a COVID-19 vaccine as long as they have not had an immediate or severe allergic reaction to a COVID-19 vaccine or to any of the ingredients in the vaccine. Learn more about vaccination considerations for people with underlying medical conditions. Vaccination is an important consideration for adults of any age with certain underlying medical conditions because they are at increased risk for severe illness from COVID-19.

Is the COVID-19 vaccine safe for people with underlying health conditions?

Clinical trials show that COVID-19 vaccines are safe and effective in people with underlying medical conditions, including those that place them at increased risk for severe COVID-19 symptoms, compared to people without underlying medical conditions.

Should you get the Covid vaccine if you have an autoimmune disease?

The American College of Rheumatology COVID-19 Vaccine Clinical Guidance recommends that people with autoimmune and inflammatory rheumatic disease (which includes lupus) get the vaccine unless they have an allergy to an ingredient in the vaccine.

Whaat happens if you mix AstraZeneca and Pfizer COVID-19 vaccines?

Researchers studied mixing and matching Pfizer's vaccine with AstraZeneca's, which is made using similar technology as J&J's. There, too, researchers found that people who got an AstraZeneca shot followed by Pfizer four weeks later produced more antibodies than those who received two AstraZeneca shots.

Can you mix boosters?;Can I mix doses of the Covid vaccine?;Can you mix boosters during the covid-19 pandemic?

The FDA is also allowing eligible Americans to mix-and-match their booster shots, which means you can choose to receive an additional dose from any of the three brands that are available.

What medications should be avoided before the COVID-19 vaccine?

It is not recommended you take over-the-counter medicine – such as ibuprofen, aspirin, or acetaminophen – before vaccination for the purpose of trying to prevent vaccine-related side effects.

Is it safe to take a different COVID-19 booster shot?

The study found that boosting with a different vaccine is safe, and that boosters increased antibody levels no matter the combination.

Can you get a different COVID-19 vaccine booster?

Mixing and matching is OK for boosters Through the FDA's authorization and the CDC's recommendation, heterologous boosting—aka “mixing and matching”—is allowed with a single dose of any of the authorized COVID-19 vaccine boosters.

Do you need two Pfizer-BioNTech and Moderna COVID-19 vaccines?

If you received a Pfizer-BioNTech or Moderna COVID-19 vaccine, you should get the same product for your second shot. You should get your second shot even if you have side effects after the first shot, unless a vaccination provider or your doctor tells you not to get it.

Is it safe to take a different COVID-19 booster shot?

The study found that boosting with a different vaccine is safe, and that boosters increased antibody levels no matter the combination.

Can you get a different COVID-19 vaccine booster?

Mixing and matching is OK for boosters Through the FDA's authorization and the CDC's recommendation, heterologous boosting—aka “mixing and matching”—is allowed with a single dose of any of the authorized COVID-19 vaccine boosters.

Are the Pfizer and Moderna COVID-19 vaccines interchangeable?

COVID-19 vaccines are not interchangeable. If you received a Pfizer-BioNTech or Moderna COVID-19 vaccine, you should get the same product for your second shot. You should get your second shot even if you have side effects after the first shot, unless a vaccination provider or your doctor tells you not to get it.

Is it safe to take the J&J/Janssen COVID-19 vaccine?

After receiving the J&J/Janssen COVID-19 Vaccine, there is risk for a rare but serious adverse event—blood clots with low platelets (thrombosis with thrombocytopenia syndrome, or TTS). Women younger than 50 years old should especially be aware of their increased risk for this rare adverse event.

When do you have side effects from the Johnson & Johnson’s COVID-19 vaccine?

These side effects usually start within a day or two of getting the vaccine. Side effects might affect the ability to do daily activities, but they usually go away in a few days.

How effective is the J&J Janssen COVID-19 vaccine?

The J&J/Janssen COVID-19 Vaccine was 66.3% effective in clinical trials (efficacy) at preventing laboratory-confirmed COVID-19 infection in people who received the vaccine and had no evidence of being previously infected. People had the most protection 2 weeks after getting vaccinated.